composition with Affinity®
The closest choice to native amniotic membrane
Never dehydrated or frozen, Affinity uses a gentle hypothermic* storage method called AlloFresh™ that preserves the product in its fresh state. In analytical testing, Affinity has been shown to retain its native tissue characteristics1,2:
Viable cells—including epithelial cells and fibroblasts1,3
Growth factors/cytokines—analytical testing has shown that the level of these factors is similar to unprocessed amniotic membrane1,4
Native extracellular matrix (ECM) structure—with multiple ECM proteins that are important for scaffolding, including collagen types I, III, V, VI, and hyaluronic acid1,3,5
The spongy layer—an abundant source of proteoglycans, glycoproteins, and hyaluronic acid1,6
*Affinity should be maintained at refrigerated temperature (between 1 °C and 10 °C).
Affinity retains a variety of growth factors and cytokines*1
Analytical studies have shown Affinity retains numerous growth factors and cytokines.
Affinity is intended to be used as a wound covering and barrier.
Please refer to the Affinity instructions for use for usage and safety information.
- McQuilling JP, et al. Int Wound J. 2017;14(6):993-1005.
- Data on file. DR-0005. Organogenesis Inc.
- Niknejad H, et al. Eur Cells Mater. 2008;15:88-99.
- Data on file. DR-0007. Organogenesis Inc.
- Mamede AC, et al. Cell Tissue Res. 2012;349(2):447-458.
- Ghatak S, et al. Int J Cell Biol. 2015;2015:834893.