Affinity® details and resources

Affinity, as a protective wound covering, supports an optimal environment for healing in a variety of wound types

As the only fresh amniotic membrane wound covering on the market, Affinity is the gold standard choice—closest to a native, unprocessed amniotic membrane.1-3

Affinity is an allograft intended for use in the management of acute and chronic wounds as well as appropriate surgical applications. Affinity may be applied as a wound covering to a variety of partial- and full-thickness acute and chronic wounds, such as:

  • Trauma wounds
  • Dehisced wounds
  • Pressure ulcers
  • Venous leg ulcers (VLUs)
  • Diabetic foot ulcers (DFUs)
  • Wounds with exposed bone and tendon

Affinity application steps4

Preparation of the wound bed:

Ensure that the wound is free of infection. Sharp debridement should be performed and extended to healthy, viable bleeding tissue. Hemostasis should be achieved, and heavy exudate controlled.

Affinity application:

Remove Affinity from the inner tray using sterile technique, like forceps

1. Remove

  1. Using aseptic technique, remove the inner tray from the outer tray
  2. Peel back the foil lid from the inner tray, remove Affinity, and place the product on the inner side of the foil lid
Identify stromal side of Affinity with a cotton swab

2. Identify

  1. Identify which side is facing up by touching the surface with a sterile cotton swab
  2. If the stromal or sticky side is up, then turn Affinity over, so that the stromal side is facing down on the foil lid. If the epithelial or non-sticky side is facing up, then you do not need to turn the product over
  3. Rinse with a sterile irrigant prior to application
Place Affinity onto the wound with the stromal side in contact with the wound bed

3. Apply

  1. Slide Affinity off the foil lid and onto the wound so that the stromal side is in contact with the wound bed
    • Two forceps can be used to help with orientation
    • Trim Affinity as needed so that it is slightly larger than the wound bed
Dressings and re-application schedule:
  1. Anchor Affinity using preferred fixation method, then cover Affinity with a primary nonadherent dressing to remain in place for up to 1 week
  2. Apply a secondary dressing that controls drainage and provides a moist wound environment
  3. Reapply Affinity weekly and continue sharp debridement as necessary
    • Offload or compress appropriately based on wound type
Affinity can be applied from the onset and for the duration of the wound, weekly, or at the discretion of the healthcare practitioner. Please confirm with your current applicable payer policies for up-to-date Affinity coverage requirements and policies.

Download the application guide

Size and storage

Affinity should be maintained at refrigerated temperature (between 1 °C and 10 °C). See the full Instructions for Use for complete storage and handling instructions.

Affinity product information


Size1.5x1.5 cm2.5x2.5 cm

Total area2.25 cm26.25 cm2

UPC #857877005139857877005115

Healthcare Common Procedure Coding System code is Q4159

Download the Affinity fact sheet

See how Affinity, as a protective wound covering, helps wounds move from stalled to closed

Review the data behind Affinity, or contact an Organogenesis Tissue Regeneration Specialist to see how the only fresh amniotic membrane wound covering can help your practice.

Contact us

Affinity is intended to be used as a wound covering and barrier.
Please refer to the Affinity instructions for use for usage and safety information.


  1. Data on file. DR-0007. Organogenesis Inc.
  2. McQuilling JP, et al. Int Wound J. 2017;14(6):993-1005.
  3. Niknejad H, et al. Eur Cells Mater. 2008;15:88-99.
  4. Allograft Tissue Information and Affinity® Instructions for Use. Canton, MA: Organogenesis Inc; 2020.