Helping wounds
move from
stalled to closed

Affinity® was proven to support healing in a prospective, multicenter, randomized controlled trial (RCT)1

  • Assessed efficacy of Affinity vs standard of care (SOC)* in 76 patients with refractory diabetic foot ulcers (DFUs) (>4 weeks' duration)
  • Digital planimetry accurately captured DFU area, depth, and volume
  • Affinity significantly improved the incidence and time to wound closure (both P<0.05)

Significantly more DFUs were closed with Affinity than SOC at 12 weeks and 16 weeks (P=0.04)1

Frequency of wound closure

60% DFUs closed at 12 weeks with Affinity vs 38% with SOC. 63% DFUs closed at 16 weeks with Affinity vs 38% with SOC. 60% DFUs closed at 12 weeks with Affinity vs 38% with SOC. 63% DFUs closed at 16 weeks with Affinity vs 38% with SOC.

*Debridement, infection elimination, dressings, and offloading by total contact casting. Silhouette® laser-assisted wound measurement device. Estimated frequency of wound closure at weeks 12 and 16; estimated from Cox adjusted survival data for wound closure.

Significantly more DFUs achieved >60% reduction in wound area (P=0.02) and depth (P=0.04) and >75% reduction in volume (P=0.06) with Affinity than SOC1

82% DFUs achieved >60% reduction in wound area vs 58% with SOC. 81% DFUs achieved >75% reduction in volume vs 58% with SOC.

*Debridement, infection elimination, dressings, and offloading by total contact casting. Silhouette® laser-assisted wound measurement device.

Median time to DFU closure with Affinity was 11 weeks. SOC failed to attain this endpoint at 16 weeks.1

Real-world evidence

In real-world patients, Affinity has been shown to reduce wound area and support closure in a wide variety of wounds from head to toe.2-4

≥65%
Wound size reduction 
at 3 weeks
Study author: Lambert • Study type: retrospective case series • Wound types: mixed (N=6 wounds)
93.9%
Wound size reduction 
at 6 weeks
Study author: Sabo • Study type: prospective case series • Wound types: mixed (N=3 wounds)
100%
Of wounds closed 
at 9 weeks
Study author: Carpenter • Study type: retrospective case series • Wound types: mixed (N=5 wounds)

Find comprehensive support with Affinity

View our provider support or talk to an Organogenesis Tissue Regeneration Specialist about supporting your practice with the only fresh, amniotic membrane wound covering.

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REFERENCES:

  1. Serena TE, et al. J Comp Eff Res. 2019. doi:10.2217/cer-2019-0142
  2. Lambert et al. Presented at: Symposium on Advanced Wound Care Fall 2015; September 26-28, 2015; Las Vegas, NV.
  3. Sabo M, et al. Chronic Wound Care Manage Res. 2018;5:1-4.
  4. Carpenter et al. Presented at: 4th Annual Innovations in Wound Healing Conference; December 7-10, 2017; Bimini, Bahamas.